Cweed LLC strives to maintain the highest standard of scientific accountability and expertise in the cannabis and hemp industries. Founded in 2017 by Wayne J M Karim (Chief Science Officer), the company offers a variety of consulting services for clients seeking insight on cultivation, harvesting, extraction, processing, refinement, product development, equipment purchasing, facility buildout, analytical testing, miscellaneous troubleshooting, and more.
We advocate for safe, potent, pharmaceutical-grade medicine containing a representative spectrum of compounds native to the plant. Scientific research asserts the efficacy of cannabis is rooted in the collective action of all its medicinal components working in concert, a phenomenon referred to as the ‘ensemble’ or ‘entourage effect’. Our methods in cultivation, extraction, processing, and formulation ensure that every aspect of the medicine is preserved without sacrificing yield or time, thus creating a superior product for patients and vendors alike.
Cweed LLC is also engaged in scientific research exploring the potential of genetically engineered photosynthetic microbes to biosynthesize exogenous cannabis terpenes. Our expert scientists are currently designing novel transgenetic protein cassettes optimized to produce individual terpenes or full-strain terpene profiles, and are developing custom photobioreactors that allow for perpetual terpene collection without costly extraction of microbial colonies.
Training & Certification
Cweed LLC offers comprehensive training sessions on a wide variety of techniques developed specifically for application to cannabis and hemp. Training sessions are typically held on-location with each client, and can be entirely customized based on available facilities, equipment, personnel, and other relevant factors. Upon successful completion of training, participants receive a Cweed Certification serving as a mark of proficiency backed by the expertise of accredited scientists and research technicians at Cweed LLC.
Available training sessions include (but are not limited to) the following topics:
Standard Operating Procedures
Cweed LLC strives to maintain the highest industry standard for scientific accountability and expertise. Our Standard Operating Procedures provide unparalleled detail and comprehensively review each aforementioned training topic in a clear and concise manner, thus ensuring all relevant information is readily accessible for current and future employees. SOPs are also offered independently of training sessions, and custom tailored SOPs are available for processes and equipment specific to individual clients.
Facility Design & Buildout
Early involvement of industry professionals often streamlines buildout and prevents costly mistakes due to oversight. Our experts offer an informed perspective for clients seeking to design and construct cultivation, extraction, production, or retail facilities. Cweed LLC regularly cooperates with architects and contractors to optimize workplace layouts for maximum efficiency, safety, and compliance with local regulations while ensuring electrical, ventilation, and plumbing specifications meet the requirements of all intended equipment.
Proper timing and discerning taste are essential when investing in equipment. The experts at Cweed LLC provide comprehensive equipment lists custom tailored to each client, and offer insightful guidance during purchasing to ensure only the best decisions are made. With careful attention to production scale, throughput capacity, and longterm goals, we develop purchasing strategies that grow along with the needs of our clients. Cweed LLC also retains exclusive discounted pricing from numerous industry-leading equipment vendors and manufacturers.
Troubleshooting & Analytics
Product potency and safety are paramount to success in the cannabis and hemp industries. Cweed LLC offers proven methods to ensure all infused products fall within specified guidelines, and can help troubleshoot persistent testing issues at cultivation, extraction, or production facilities. Training, method development, data interpretation, and referral services are also available for advanced analytical instruments such as: HPLCs, NMR, GC-MS, LC-MS and IR.
Advanced Research Topics
Thinking of starting a cannabis research initiative? The scientists and technicians at Cweed LLC have extensive experience in a wide range of disciplines applicable to virtually any type of scientific or medical research. Fields of expertise include Medicinal Chemistry, Microbiology, Genomics, Organic Chemistry, Molecular Biology, Chemical Genetics, Analytical Chemistry, and Botany. Parties interested in joint research ventures are encouraged to contact us.
Wayne J M Karim
Wayne J M Karim is a medicinal chemist and cannabis specialist with training in total chemical synthesis, analytical chemistry, pharmaceutical compounding, molecular biology, and microbiology. Wayne completed his studies for Bachelor’s of Science in Biology at the University of California Riverside, and his studies for Master’s of Science in Medicinal Chemistry at the University of San Francisco. Following employment as Director of Extraction for the world’s first medical cannabis company, Tikun Olam, Wayne founded Cweed LLC where he currently serves as Chief Scientific and Chief Operating Officers. Cweed LLC currently provides professional consulting services to the global cannabis and hemp industries, while also exploring the potential of transgenetic photosynthetic microbes to engage in exogenous cannabis terpene biosynthesis through research efforts under the direction of their CSO.
Dr Andrew J Defries PhD
Dr. Andrew Defries PhD is a botanical chemist with training in human physiology, pharmacology, genetics/genomics, and plant physiology. Andrew completed his graduate degree in Plant Chemical Genetics from agricultural focused University of California Riverside in 2013. Seeking post doctoral work with cannabis Andrew began his career in an analytical testing lab for Absolute Extracts (Santa Rosa, CA). Shortly thereafter, in 2016, he was integral for the debut state licensed Medical Marijuana provider Bloomfield Industries in New York.
At Bloomfield Andrew utilized his botanical expertise to launch the cannabis plant population and completed the build of both the CO2 extraction and analytical laboratories. Andrew has experience overseeing quality and analytical testing from cultivation to extraction at a production scale. More recently Andrew was the Director of Quality and Analytics for the launch of the national cannabis brand Tikun Olam USA now known as Tikun.
In addition to this experience Dr. Defries has been a consultant for several startups with large scale CO2 Cannabidiol (CBD) extraction and refinement projects across the US in Colorada, Pennsylvania, New York, and Oklahoma. Through his work he has observed several regional opportunities for hemp in the North East coast region of the United States. Andrew founded 710 Vermont LLC in 2019 and purchased 17.75 acres of arable land in the Northeast Kingdom of Vermont to grow hemp. An additional 13.5 acres will be purchased by April 3, 2019. The 31-acre crop is intended to be sold wholesale as a manicured flower and/or extracted to be sold wholesale as a formulated hemp product.